The median age of death for a person with PWS is ages 30 years . A 2022 review of studies on morbidity and mortality found that the average age of death may be closer to 21 years old. An individual may live a shorter or longer life depending on a number of factors.

Additional features of this condition include distinctive facial features such as a narrow forehead , almond-shaped eyes, and a triangular mouth; short stature; and small hands and feet . Some people with Prader-Willi syndrome have unusually fair skin and light-colored hair .

Scoliosis and kyphosis are common and may be severe. Hyperphagia, low muscle tone, respiratory and sleep problems, including excessive daytime sleepiness and lack of energy, exacerbate the tendency to become morbidly obese in the adolescent years, which is the major cause of mortality in adults with PWS.

There's no cure for Prader-Willi syndrome, but your child will have support from healthcare professionals who will help you manage the condition.